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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2172b7a0d0514c257adc05ce71d75619e5a805c8aa552dcafa6262b2c0f5ce36' 
  AND token = 'zEH2P5/K1Zv7qZ24NSNoyA66Nb3eNbdzrweGDfGMylg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}