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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a75a966758241c02273288cf491a65ca82654f515b00a0f890e149e5eeadc70' 
  AND token = 'U5d8rGuCb5U+xt7bmDwP1RS54ccE+rzS29tA8L9KfdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}