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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f9cb8955c5a7b4c5f07450d1ccef50b8edc60d4c6ab589e77dbe1533e636e48' 
  AND token = 'fUG3QUMc3Hsq9kUqTPu6vEgdg+rFotI25rj+D5n9dfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}