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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b382d240f7d3a903404e8c0f9f6638f350742b32e682c0e7acf857cc0307d94' 
  AND token = 'FdxP3bphPE27gjahcwxHWw57yL1Tc42UWoY32K9bPKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}