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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b428235c91c2b452bb5bc1ef4411a3776de22b9c97e19b8a795afe5b6e89b8' 
  AND token = '2SdEjWGMs1x1K2R0EqpUR2/k4E24TfY51iMhQ+BN8KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}