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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4505ef8a7b76c97dbd2734065134247417f49f6168e7893c7a347a8c02e1793e' 
  AND token = '5BWkQnpnBeu2TfA6PTpRYu7aSVWw6gzyGI9fvqxxZtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}