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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4f12796d8f6233fad0dcf79e7cad93362741ab5ff42c135ff5d25462cac2d41' 
  AND token = 'EuKc+rG14StVO7Y5+yt2HHdgXHlq4++s7ob3XTAn8lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}