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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df86846aa717d57f2a23ac075b247b3fc5318bc26563b8e7f56535a085f569dc' 
  AND token = 'S+jJCcd46N1L9RT3iknkG96ZcKmd66FGDF+xYKmMUew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}