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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735d51dbd4a2f60dbe999d86d6100a9ddd4089ea08fdd211930af5b0b09ac5d4' 
  AND token = 'FCq0sBwGQrx4dZArEXydDTXKalGeIhdbVposZ1MbPBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}