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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4b819f59d28c02b0bc6a5f49e0bfdadb463ccad234795c779df265dd90bbb9' 
  AND token = 'jPrVYRE9ANjh11VN88hnEWa/1no+0dYgc14NA/jHqNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}