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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed37cbda39d79b9db8248dfd32c82760f2057ea0e297e5201f96a26e176bed0' 
  AND token = 'KO3vfZrX2zqUFfdlSFNWZzRy8OGrrk2LkREqRP5Xq4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}