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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3d65754fc772e7baeeba3dd4eaf9b1fac8125c538296f6aca75dd5d72de9d29' 
  AND token = 'efiVD3YX/zeiSokXEe/47yjWA3vc/jFk6OP+bIdRmC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}