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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '154e2ef3468e3c370a56c450d16d02521d917f7e682dec8e1cb37ee03da8ad57' 
  AND token = 'LWIypvHSn4RFO7BugZOTULXLiW8dyiBc6x0sVA8ESn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}