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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93c54a1a1f014361aaee4610ca3b6e389a3927228a6cc648dc1c6b55f0e37c16' 
  AND token = 'uZCSsJK/tOap0UC2cD+LwQ5MhsaBhmq4uK2Bvv4R4PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}