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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c277f7ea395cc5f926589a06c17621016b3cc3e8ec8130344b4e63715f4dfaa5' 
  AND token = 'KXDmfZGcjT+IuO5/rCncmiw18rqoQX+C+9T5lkeuAKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}