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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48108ed4c9719b38e8a1597ebefb46f3521788f5578d3b6aebdb178d43c4248d' 
  AND token = 'd7F2hwob9BkarCuPkGL+eQkFGilDo1/MlifQfOxoZX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}