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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0978af4fd8e37b24c26219789031491219033ca864f7a60e17b1c94fe394db86' 
  AND token = 'gtN5O59hS6C3yiabElhF9f+P1/PpLvxFTvG63uZXVE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}