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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a997cae66371e52059c82f7ed1cb7c98af47632e26d7911869d3e02038f487' 
  AND token = 'wfyxcQYKD7o/zMHe927mWLVj0Nnd3w/8F8Kxz+Ck99o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}