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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9f0757828cde9a072deea49582daf648377c62d73110e4fd7e69bc7b9fb64bd' 
  AND token = '6uo3knB+I0a4Jvg69bOk00gCjQnwThpRgCLoaWRCvnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}