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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f57aec0c48d6dd32170626bd90292445e233ef97445dfcaf53af519e01eb464' 
  AND token = 'tGTCvGQrWIwnq7HGTuEcaEvOwK3zkxphOclydZt9ZPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}