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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1bc9caa3b843c09f9077197b8c595699921cefe87c5f826b538bb257ec7a8af' 
  AND token = '0wpm9KTMPoqMILFnaPEK2me0yD3gx2SbttWQJgy6EUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}