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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '167d34535b16055a97c08be4d7f971dbfc1ab0aab1f7738cd01896618c2281a6' 
  AND token = 'F2TlFTCoOvd/UO4KZf9dFoIU7t5bNOXxhMHAXGRq/RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}