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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27177f1a33c0340d3c8e93046fae5cb438328ae13a67a9e0c234f6bd47cb1b18' 
  AND token = 'v8HVkt2wZONCKmMi8lhpWpv4ssqO9BKXdwlquoCc6bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}