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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8659c8a2d3bef21641ea0671ed829b001099d9fddb39791507c562f60d529a9' 
  AND token = 'qbAjDaYBv6cd5nYeWtPDInYjVpFcjK6/KkE/OcdPiRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}