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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241203633bffc0271a305e1db03e889206db0de96a138809266c9cdf71265691' 
  AND token = '21hfY1WarpOUA2wNWuRTBkKZ2m5z63/ME2nzPx1uxDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}