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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '160674f9de980ecba6773309f144b23fb9b99b04a48d312b0e131f7bfb7d0347' 
  AND token = 'ik2AwjTrOxy3+vC3XG8AZd6ZeOPocN998VvyaUdQUIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}