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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e0288957f137590afe2d2f884b8a540a2d3dc189864ac7050e6f65a027579bc' 
  AND token = 'yeuD9Jk8nWioArMQq9ZpFCrcS4xRb+X/5EbJNSKaB4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}