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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbc8dc49fbddbabc1cbc976a547b165a99729c7f134cf91881053d280ca47ed4' 
  AND token = 'Fozkc5BW/oB9Kn63I/dnEl+iY/V+Sy0iWaBWyu8lH90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}