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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df273eac97e4ca17c3d0d0a2fdf675af75da3d45d976dfd338f86a80a36856f0' 
  AND token = '/i0WGnYqNQurOaAIYzYavzlh5H16PL11rsY13ZGtGs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}