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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e68111a59e63def4e8b2d7ec4711ec7fe893654040394645b9fc5bb4c836e647' 
  AND token = 'YQjIssZi/ATWMmBt/3ErxmT/mbx20pL4yzAuHMBb33Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}