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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e02f531e80c0f170d8e49074b2ac19ed84a46bec0a2954e439bcfd1859890740' 
  AND token = 'Yu5gYaMO1/CsCBLgnp0/Tavt7A3mTv1MBM0IEG6t9wU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}