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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a075429be93e122ed11ef78cf168f69acde89497597a6f5ff2bae043a97c80' 
  AND token = 'WMIam3+yWWciQGOBa2h46FSs1tZVSybrstM1VAq4jPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}