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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5e14b20667efa6328d23f3169741df71bb7d46b6cabcbb44893fb5b377d1272' 
  AND token = 'fvNtYY9Z6MhJtqXb8oEnp2XPVlivCS0EA5BRKJiEjbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}