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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05dc8112ec1d3e6be43920f4935590245782237ed0463cd4924aff47185de65c' 
  AND token = 'ZSdGOx1+l4Se7PhdmM0MC3UDaRe1Q4KPhcXUQjvFwbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}