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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33cfe1cebcb9758a3f57d185f8262252e305baf6557e8d4be067febe081276a1' 
  AND token = 'JWc2RPigA3psk5eEP0ZIdT6mG9wyOGtHyVXyM5nCPMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}