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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff60b95826c53bea1f622ddd4d6aaa0a6da814f95c2c978d85d7db25839ded5' 
  AND token = 'xAC9kb0n9SUHoTfkt8GZ5rgKhGqjxPhSdnCVKdJsE4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}