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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b13d2b66b3e440bd9d707d67be97c6bd50d1187c5469e1c71e82a9b407f080' 
  AND token = 'gfGhB9EFzfP1GMiF7wCvZUNfO8qEio367PapUBuyIpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}