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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165d0e3dab8e0eaa12079ac6a181ffe4dd89fe85aeafb770a52b4e22e7b47ca0' 
  AND token = 'xV2uU0QJ7PqCl2vkjXW1jCR+EaTVUfbzus+0Vo6W1mI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}