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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de9989181f2935c9bc0c143c0963ce3cd6eb8f696e1e3cdef85f0984f1c7b8a' 
  AND token = 'gOLTRBwIHJOxvOhDeXRQY7G9naHmO/BjTO4Ps1ie6/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}