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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac4154403dacdbd88292f0d0ec8f2d1f5a36636c0100cf68a450223dc236f0c' 
  AND token = 'P2US59TgRs3zw7+cC0b2VwjmC9Kl1yel56kx1Snu1DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}