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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af28d3c5d8dafeb836f43f2f21c64dd58aae3373f4ec21b0d0bdbd7c2043f931' 
  AND token = 'DXikWp+pFy5cDKv2pWJ1zWoCJCsFEoluqh1GR3IMNXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}