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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21faf506b2fdd842ffdcceff7344fa20e8c74d4840418c03c076ae5331534a00' 
  AND token = 'hAhKGlYN8AojHfx31G8D/DEhiw6rwHlxSnstYKuOpL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}