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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a7930308b93d75283b255cab5ffa8d63504e25618526a75900b0171314c0456' 
  AND token = 'Tb6IViY6j1iy1XCESQyzolV0QHlcu+qbuJrOdmXmwiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}