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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86c7925acd2e4d41c46157cb3725adfe413426b29251fd4de0b2d1c2130f1579' 
  AND token = '2H9MfKEIl9ZDsvh1DpJVsdlXh+3G7MUJbb4hFqXtAhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}