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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5046fe47eb1edbcc68ef1cc1367e4b00d785e8a2f747f487fd9d38de9216f4a6' 
  AND token = 'Xd6VjIoR4pv/VD4wLLVuxT3xMuqnX06XWedFSSSeH9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}