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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f501a34f7357862b1bfc5b2e04ada0a1accc380a5a5cdf7aabd8a34961107253' 
  AND token = 'EuLvC/0/7hvxl1Fy0hkaoWEsFDhXfhAEBg0iuK4EmU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}