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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4865df1e40139b0dd48736e7a8156d4c2cc684612a86e2f101bbc2c58b0c5efb' 
  AND token = 'c6B+eE3HBjC4GOIaDvLJpd4KxYKw8ZDXRkq7a16QCxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}