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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b3456f9428b713b32f9102a10a3be27f8c3a99b3d20cf5eaa051a33aa8bac64' 
  AND token = 'tM2IpnAhK9Bd+ZePtmH7c05rciapY6BoGlO2NOrOgmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}