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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e126ac0a7b64e90fcaf5818be9e0eb8a21b068c10c105fe1290164ac1dbbc3b' 
  AND token = 'qFzhXNE2v7gLRtdWrr2fh90kl/P/+hPtgpZj9eJTlF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}