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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e459e5f0dc4e8a50e25caee43690c4a31cf8a8f0399e1f01440a02287b26869' 
  AND token = '/vAeCmdmZKGWuGZrAI9YyoKSxu+8uk+mKFTdw8dkMWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}